The event was dominated by Alejandro G. Iñárritu's The Revenant and Ridley Scott's The Martian.
Donoghue was the first person Larson thanked when accepting the award.
It's the fourth time Ricky Gervais has hosted the Golden Globes ceremony but there were still a few shocks and surprises from the comedian. The Martian did win best comedy film and best actor in a comedy for star Matt Damon.
And when organizers tried to cut off her speech, she hit back.
The actor didn't get to take a trip to the stage as Empire lost in the Best Television, Drama category to Mr. Robot, but he was able to cheer on his co-star Taraji P. Henson as she won for Best Performance by an Actress in a Television Series, Drama. This time, he mentions the Oscars, which prompts Lawrence to cut him off again saying, "We're at the Golden Globes".
"Wait a minute. I waited 20 years for this".
Supporting Actress, Motion Picture: Kate Winslet, 'Steve Jobs'.
Pixar and Walt Disney Studio's Inside Out won the award for Best Motion Picture in the Animated category.
Picture, Musical or Comedy: "The Martian". Gosling was just playing, of course.
For viewers at home, short of Ricky Gervais' acerbic insults and watching famous people get drunk, the show is mostly a snooze. According to Entertainment Weekly magazine, NBC didn't give Gervais restrictions to his jokes.
It should not be a shock to anyone that the Golden Globes have become a joke.
Best actress Golden Globe victor Jennifer Lawrence has been scolded on Twitter following an awkward confrontation with a journalist in the press room.
Fox had the top two films at the Golden Globes.
In the best picture category, a pair of films seen as Globes favorites fell flat on Sunday, but are still expected to earn some Oscar nominations. Poor Tomlin even missed out twice over, having been nominated for best actress in a musical or comedy for Netflix's Grace and Frankie, the award going to Rachel Bloom in Crazy Ex-Girlfriend.
"If you put your phone down, you'd know that", she said. "But music worked out first".
Yes, Gervais upheld his reputation "as one of the most shameless awards show emcees in recent memory", says Caroline Framke on Vox.
The award for Best Original Score went to Ennio Morricone for the Quentin Tarantino film The Hateful Eight. The nominations for the awards were announced earlier on December 10, 2015. Foxx also introduced his daughter Corinne as Miss Golden Globes 2016.
Best sight gag of the night: When the camera cut to TV comedy nominee Aziz Ansari, he was reading a book titled, "Losing to Jeffrey Tambor with Dignity". The award went to Bernal, though, not Tambor.
So while he is great in "The Revenant" and it's a fine film, DiCaprio and the others didn't win due to their acting.
For his efforts over the years, Denzel Washington clinched the Cecil B. DeMille lifetime achievement prize.
Other key winners included Sylvester Stallone, 69, who received a standing ovation as best supporting film actor for reprising his iconic role as boxer Rocky Balboa in "Creed".
Texas judge lowers bond for mother of 'affluenza' teen to $75000
The affluenza diagnosis, which is not recognized by the American Psychiatric Association, was widely ridiculed. He said that his mother's bank account, which contains about $100,000, has been frozen by authorities.
